Uses

Topical urea is indicated for the debridement and promotion of healing of hyperkeratotic skin lesions. It is effective for dry rough skin, psoriasis, eczema, ichthyosis, xerosis, keratosis, and for treating thickened, damaged, or ingrown nails.

Do not use if

Contraindicated in patients with known hypersensitivity to urea or any other ingredient in the formulation. Avoid application on acutely inflamed, infected, or broken skin.

Side effects

Transient stinging, burning, itching, or irritation may occur at the application site, typically resolving without intervention. These effects are more common at higher concentrations.

Warnings

For topical use only. Avoid contact with eyes, lips, and mucous membranes. Keep out of reach of children. Store at controlled room temperature (20–25°C).

How it works

Urea dissolves the intercellular cementing substance of the stratum corneum, causing gentle loosening and removal of the hyperkeratotic layer. This keratolytic and hydrating action restores softness and flexibility to thickened skin. Higher concentrations also exert proteolytic effects.

Storage

Store at 20–25°C (68–77°F). Do not freeze. Keep container tightly closed.