- Active ingredient
- diflucortolone valerate+isoconazole nitrate
- Form
- cream
- Manufacturer
- misr > pharmacare
- Route
- topical
Uses
Combination topical preparation used for inflammatory skin conditions complicated by or at risk of fungal infection, such as tinea corporis with secondary inflammation, intertrigo, and other dermatomycoses with concurrent dermatitis.
Do not use if
Contraindicated in cutaneous tuberculosis, viral skin infections including herpes simplex and varicella, and hypersensitivity to any component. Not for ophthalmic use.
Side effects
Local side effects include burning, itching, and skin atrophy with prolonged use. Isoconazole may occasionally cause contact sensitization. Systemic effects from diflucortolone valerate are possible with extensive application or occlusion.
Warnings
Limit treatment duration, especially in intertriginous areas and in children. Do not use in skin infections not responsive to antifungal therapy without reassessing the diagnosis. Avoid prolonged use on the face.
How it works
Diflucortolone valerate is a potent topical corticosteroid that suppresses inflammation and pruritus. Isoconazole nitrate is a broad-spectrum imidazole antifungal that inhibits ergosterol synthesis in fungal cell membranes, leading to fungal cell death.
Storage
Store below 25°C, away from direct sunlight. Do not freeze. Keep the tube tightly closed after use.
