prandaglim plus 25/30 mg 30 f.c. tabs
برانداجليم بلس 25/30مجم 30 قرص
alogliptin+pioglitazoneThe published official price. Pharmacies may differ slightly.
- Strength
- 25/30 mg
- Form
- tablet
- Manufacturer
- eva pharma
- Route
- oral.solid
The medical information below is guidance and may be incomplete or wrong. Do not change your medicine or dose based on it — ask a pharmacist or doctor.
Uses
Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Not recommended for type 1 diabetes or diabetic ketoacidosis.
Do not use if
Contraindicated in patients with NYHA Class III or IV heart failure and in those with a history of serious hypersensitivity to alogliptin or pioglitazone.
Side effects
Common adverse effects include upper respiratory tract infection, nasopharyngitis, and peripheral edema. Serious risks include congestive heart failure, pancreatitis, hypersensitivity reactions, and hepatic effects.
Warnings
Thiazolidinediones including pioglitazone can cause or worsen congestive heart failure; monitor closely after initiation. Risk of pancreatitis; discontinue if suspected. Risk of bladder cancer with prolonged use of pioglitazone.
How it works
Alogliptin inhibits DPP-4, increasing incretin hormones (GLP-1 and GIP) that stimulate glucose-dependent insulin secretion. Pioglitazone is a PPAR-gamma agonist that improves insulin sensitivity in peripheral tissues and the liver.
Storage
Store at 25°C (77°F); excursions permitted to 15–30°C (59–86°F). Keep container tightly closed and protect from moisture and humidity.