Uses

Indicated for certain EGFR mutation-positive metastatic non-small cell lung cancers and for metastatic squamous NSCLC after platinum-based chemotherapy.

Do not use if

No specific absolute contraindications are listed, but hypersensitivity to the drug requires discontinuation.

Side effects

Common adverse effects include diarrhea, rash, skin reactions, mouth inflammation, and nail disorders. Serious pulmonary, hepatic, and gastrointestinal complications may occur.

Warnings

Monitor for severe diarrhea, skin toxicity, interstitial lung disease, hepatic injury, and dehydration.

How it works

An irreversible ErbB family tyrosine kinase inhibitor that blocks EGFR, HER2, and HER4 signaling pathways.

Storage

Store at 20–25°C in the original container protected from moisture.