reiferon retard 160mcg/1.2ml vial
ريافيرون ريتارد 160مكجم/1.2مل امبول
peginterferon alfa - 2aThe published official price. Pharmacies may differ slightly.
- Strength
- 160mcg/1.2ml
- Form
- vial
- Manufacturer
- mina pharm
- Route
- injection
The medical information below is guidance and may be incomplete or wrong. Do not change your medicine or dose based on it — ask a pharmacist or doctor.
Uses
Peginterferon alfa-2a is indicated for the treatment of chronic hepatitis C (CHC) in adults, in combination with other antiviral agents, and as monotherapy only when other HCV drugs are contraindicated or not tolerated. It is also indicated for chronic hepatitis B (CHB) in adults with HBeAg-positive and HBeAg-negative disease, and in combination with ribavirin for CHC in pediatric patients aged 5 years and older.
Do not use if
Contraindicated in patients with hypersensitivity to alfa interferons or any component of the product, autoimmune hepatitis, hepatic decompensation before or during treatment, and neonates/infants due to benzyl alcohol content.
Side effects
Common side effects include flu-like symptoms (fatigue, fever, headache, myalgia), psychiatric effects (depression, irritability), neutropenia, thrombocytopenia, and alopecia. Serious life-threatening reactions include severe neuropsychiatric disorders, autoimmune disorders, ischemic events, and severe infections.
Warnings
Carries a boxed warning for risk of serious and potentially fatal neuropsychiatric, autoimmune, ischemic, and infectious disorders. Patients must be monitored closely and therapy withdrawn if severe reactions develop. Combination with ribavirin is contraindicated in pregnancy.
How it works
Pegylated recombinant interferon alfa-2a is an inducer of the innate antiviral immune response. It stimulates production of effector proteins such as serum neopterin and 2',5'-oligoadenylate synthetase, inhibiting viral replication. Pegylation extends the half-life to allow once-weekly dosing.
Storage
Store refrigerated at 2°C to 8°C. Do not leave out of refrigerator for more than 24 hours. Do not freeze or shake. Protect from light.