Uses

Used with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Do not use if

Contraindicated in severe renal impairment, metabolic acidosis, diabetic ketoacidosis, and hypersensitivity.

Common effects include diarrhea, nausea, abdominal discomfort, bloating, and vitamin B12 deficiency with long-term use.

Rare but serious lactic acidosis can occur, particularly in patients with renal impairment.

Metformin decreases hepatic glucose production, reduces intestinal glucose absorption, and improves insulin sensitivity.

Store at room temperature away from moisture.