Uses

Used for estrogen replacement therapy and management of estrogen deficiency symptoms.

Do not use if

Thromboembolic disorders, estrogen-dependent cancers, severe liver disease, or unexplained vaginal bleeding.

Headache, breast tenderness, irregular bleeding, nausea, and fluid retention may occur.

Smoking and cardiovascular risk factors increase the risk of serious vascular events.

Prodrug converted to estradiol, providing estrogenic effects in target tissues.

Store at room temperature.