- Active ingredient
- betamethasone dipropionate
- Strength
- 0.05%
- Form
- cream
- Manufacturer
- memphis > schering plough
- Route
- topical
Uses
Indicated for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients 13 years and older. Effective for conditions such as psoriasis, eczema, contact dermatitis, and other inflammatory skin disorders.
Do not use if
Contraindicated in patients with hypersensitivity to betamethasone dipropionate, other corticosteroids, or any ingredient in the preparation.
Side effects
Local adverse effects include skin atrophy, telangiectasia, bruising, striae, and stinging (reported in ~0.4% of adults). In pediatric patients, skin atrophy, telangiectasia, and bruising are more common. Systemic effects (HPA axis suppression) may occur with prolonged or extensive use.
Warnings
Prolonged use may cause reversible HPA axis suppression. Avoid use on the face, groin, or axillae. Do not use under occlusive dressings unless directed by a physician. Not for ophthalmic use. Use with caution in pediatric patients due to higher systemic absorption per body surface area.
How it works
Betamethasone dipropionate is a high-potency synthetic corticosteroid. It exerts anti-inflammatory, antipruritic, and vasoconstrictive actions through cellular signaling modulation. The precise mechanism in dermatoses involves suppression of inflammatory cytokines and modulation of immune cell function, though the exact pathway is not fully elucidated.
Storage
Store at 20–25°C (68–77°F). Protect from freezing.
