Sinopril-co 12.5/20mg 30 tab
سينوبريل كو 12.5/20مجم 30 قرص
hydrochlorothiazide + lisinoprilFrom the official published price list, updated twice a day. Pharmacies may differ slightly.
Save 25.5 EGP (24%) with an identical equivalent
Same active ingredient, strength, form and pack size: Lisitens 12.5/20mg 30 tab (79.5 EGP)
The medical information below is guidance and may be incomplete or wrong. Do not change your medicine or dose based on it — ask a pharmacist or doctor.
Uses
Indicated for the treatment of hypertension to lower blood pressure and reduce the risk of cardiovascular events such as stroke and myocardial infarction. The combination is used when monotherapy with either agent alone is insufficient.
Do not use if
Contraindicated in patients with a history of ACE inhibitor-related angioedema, hereditary or idiopathic angioedema, hypersensitivity to sulfonamides (for the thiazide component), anuria, and in pregnancy due to fetal toxicity risk.
Side effects
Common side effects include cough (from lisinopril), dizziness, headache, fatigue, and electrolyte disturbances such as hypokalemia (from hydrochlorothiazide). Angioedema, though rare, is a serious adverse effect of the ACE inhibitor component.
Warnings
Discontinue immediately upon detection of pregnancy due to risk of fetal injury and death. Monitor renal function and serum potassium regularly. The ACE inhibitor component carries a risk of angioedema, which may be life-threatening if it involves the larynx.
How it works
Lisinopril inhibits angiotensin-converting enzyme (ACE), reducing angiotensin II formation and aldosterone secretion, promoting vasodilation and sodium excretion. Hydrochlorothiazide is a thiazide diuretic that increases urinary sodium and water excretion. Together they produce complementary antihypertensive effects and counterbalance each other's electrolyte effects.
Storage
Store at controlled room temperature away from moisture and heat. Keep in tightly closed containers as directed on the product labeling.