Uses

Indicated for the treatment of functional circulatory disorders and orthostatic hypotension. Used to increase blood pressure in patients with symptomatic low blood pressure including acute hypotensive states.

Do not use if

Contraindicated in hypertension, hyperthyroidism, severe arteriosclerosis, phaeochromocytoma, narrow-angle glaucoma, and concurrent use with non-selective MAO inhibitors.

Side effects

May cause palpitations, tachycardia, headache, tremor, and anxiety. At higher doses may cause hypertension, arrhythmias, and angina. Reflex bradycardia may occur.

Warnings

Use with caution in patients with cardiac disease, diabetes, or prostatic hypertrophy. Monitor blood pressure during treatment. Interactions with MAO inhibitors and tricyclic antidepressants may cause dangerous hypertensive crisis.

How it works

Etilefrine is a sympathomimetic amine with both alpha- and beta-adrenergic agonist properties. It increases blood pressure by increasing cardiac output (beta-1 effect) and causing peripheral vasoconstriction (alpha-1 effect). It is used orally for chronic management of hypotension.

Storage

Store at room temperature, below 25°C, away from light and moisture. Keep out of reach of children.