Replitza 1/500 mg 30 f.c. tabs
ريبليتزا 1/500مجم 30 اقراص
metformin + repaglinideFrom the official published price list, updated twice a day. Pharmacies may differ slightly.
Save 23 EGP (64%) with an identical equivalent
Same active ingredient, strength, form and pack size: Magicnorm 1/500 mg 30 f.c. tabs (13 EGP)
The medical information below is guidance and may be incomplete or wrong. Do not change your medicine or dose based on it — ask a pharmacist or doctor.
Uses
Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who are not adequately controlled on metformin or repaglinide alone.
Do not use if
Metformin is contraindicated in patients with eGFR below 30 mL/min/1.73m², hepatic impairment, or acute illness at risk of lactic acidosis. Repaglinide is contraindicated in type 1 diabetes and diabetic ketoacidosis.
Side effects
Common side effects include hypoglycemia, diarrhea, nausea, vomiting, and abdominal discomfort. Lactic acidosis is a rare but serious risk with metformin. Repaglinide may cause weight gain.
Warnings
Withhold metformin before iodinated contrast procedures and restart only after renal function is confirmed adequate. Monitor renal function regularly. Risk of hypoglycemia is increased with repaglinide especially when meals are skipped.
How it works
Metformin reduces hepatic glucose production and improves peripheral insulin sensitivity without causing hypoglycemia. Repaglinide is a meglitinide that stimulates insulin secretion by closing ATP-sensitive potassium channels in pancreatic beta cells in a glucose-dependent manner.
Storage
Store at room temperature (15–30°C), away from moisture and heat. Keep in original container.