thiophenicol 250mg 16 f.c. tab
ثيوفينيكول 250مجم 16 قرص
thiamphenicolThe published official price. Pharmacies may differ slightly.
- Strength
- 250mg
- Form
- tablet
- Manufacturer
- sanofi
- Route
- oral.solid
The medical information below is guidance and may be incomplete or wrong. Do not change your medicine or dose based on it — ask a pharmacist or doctor.
Uses
Thiamphenicol is a broad-spectrum antibiotic indicated for the treatment of susceptible bacterial infections including respiratory tract infections, urinary tract infections, and sexually transmitted infections such as gonorrhoea and chlamydia.
Do not use if
Contraindicated in patients with pre-existing haematological disorders, renal or hepatic impairment, and known hypersensitivity to thiamphenicol or chloramphenicol. Contraindicated in neonates and during pregnancy and breastfeeding.
Side effects
The most significant adverse effect is reversible bone marrow suppression causing anaemia, leukopenia, and thrombocytopenia. Gastrointestinal effects include nausea, vomiting, and diarrhoea. Unlike chloramphenicol, aplastic anaemia is rarely associated with thiamphenicol.
Warnings
Monitor blood counts during therapy due to risk of reversible bone marrow suppression. Avoid use in patients with severe renal impairment or those requiring high-dose or prolonged therapy without haematological monitoring.
How it works
Thiamphenicol is a semisynthetic broad-spectrum bacteriostatic antibiotic, a structural analogue of chloramphenicol. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit and blocking peptidyl transferase activity. It is active against a wide range of Gram-positive and Gram-negative organisms.
Storage
Store below 25°C in a dry place, protected from light. Keep in original packaging.