- Active ingredient
- etofenamate
- Strength
- 5%
- Form
- gel
- Manufacturer
- sigma > pharma cure pharmaceuticals
- Route
- topical
Uses
Topical non-steroidal anti-inflammatory drug used for the relief of local pain and inflammation in musculoskeletal conditions such as sprains, strains, tendinitis, and minor soft-tissue injuries.
Do not use if
Contraindicated on broken or infected skin and in patients with known hypersensitivity to NSAIDs. Avoid in the third trimester of pregnancy.
Side effects
Local reactions at the application site include erythema, pruritus, and burning sensation. Systemic absorption is low but prolonged use may rarely cause gastrointestinal or renal effects.
Warnings
Avoid contact with eyes and mucous membranes. Not recommended for use under occlusive dressings for extended periods. Wash hands after application.
How it works
Etofenamate is an ester prodrug of flufenamic acid, an anthranilic acid derivative NSAID. After percutaneous absorption it is hydrolysed to flufenamic acid, which inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing prostaglandin synthesis and thereby producing anti-inflammatory and analgesic effects.
Storage
Store below 25°C. Do not refrigerate. Keep tube tightly closed.