Uses

Used for serious bacterial infections including respiratory, urinary, intra-abdominal, gynecological, skin, bone, joint, bloodstream, and cardiac infections.

Do not use if

Contraindicated in patients with hypersensitivity to imipenem, cilastatin, or formulation components.

Side effects

May cause nausea, diarrhea, rash, hypersensitivity reactions, and seizures in susceptible patients.

Warnings

Serious hypersensitivity reactions and seizures may occur. Use cautiously in patients with CNS disorders.

How it works

Imipenem is a broad-spectrum carbapenem antibiotic, while cilastatin inhibits renal metabolism of imipenem.

Storage

Store according to manufacturer instructions before reconstitution.