kadomet 250mg 30 tab
كادوميت 250 مجم 30 قرص
methyldopaThe published official price. Pharmacies may differ slightly.
- Strength
- 250mg
- Form
- tablet
- Manufacturer
- kahira
- Route
- oral.solid
The medical information below is guidance and may be incomplete or wrong. Do not change your medicine or dose based on it — ask a pharmacist or doctor.
Uses
Indicated for the treatment of hypertension. Particularly useful in the management of hypertension during pregnancy (one of the preferred antihypertensives in pregnancy).
Do not use if
Contraindicated in patients with active hepatic disease (acute hepatitis, active cirrhosis), history of methyldopa-related liver disorders, hypersensitivity to any component, and in patients receiving MAO inhibitor therapy.
Side effects
Common side effects include sedation, fatigue, headache, and dizziness, especially at the start of therapy. May cause dry mouth, bradycardia, hepatotoxicity, and a positive Coombs test with potential hemolytic anemia.
Warnings
Monitor liver function periodically; discontinue if signs of hepatic damage appear. Hemolytic anemia may occur; monitor blood counts. Positive Coombs test is common but does not always indicate hemolysis. Use with caution in renal impairment.
How it works
Methyldopa is a centrally acting antihypertensive that is metabolized to alpha-methylnorepinephrine, which stimulates central inhibitory alpha-2 adrenergic receptors in the brainstem, reducing sympathetic outflow and thereby lowering peripheral vascular resistance and blood pressure.
Storage
Store at controlled room temperature below 30°C, protected from light and moisture.