bilopropin 5/5 mg 30 tabs
بيلوبروبين 5/5مجم 30 قرص
bisoprolol fumarate+amlodipineThe published official price. Pharmacies may differ slightly.
- Strength
- 5/5mg
- Form
- tablet
- Manufacturer
- marcyrl pharmaceutical industries (mpi)
- Route
- oral.solid
The medical information below is guidance and may be incomplete or wrong. Do not change your medicine or dose based on it — ask a pharmacist or doctor.
Uses
This combination of amlodipine (a dihydropyridine calcium channel blocker) and bisoprolol (a cardioselective beta-1 blocker) is indicated for the management of hypertension and stable angina pectoris, particularly in patients requiring both drug classes for optimal blood pressure and heart rate control.
Do not use if
Contraindicated in cardiogenic shock, decompensated heart failure, sick sinus syndrome, high-degree AV block (without pacemaker), severe bradycardia, and hypersensitivity to either component. Avoid in patients with severe asthma or COPD.
Side effects
Common side effects include edema (mainly ankle swelling from amlodipine), fatigue, bradycardia, dizziness, and headache. Cold extremities and bronchospasm may occur due to the beta-blocker component.
Warnings
Do not abruptly discontinue bisoprolol; taper dose gradually to avoid rebound hypertension or angina. Monitor for signs of heart failure. Use with caution in diabetes (may mask hypoglycemia symptoms). Avoid in severe peripheral arterial disease.
How it works
Amlodipine blocks L-type voltage-gated calcium channels in vascular smooth muscle and cardiac cells, causing vasodilation and reduced cardiac afterload. Bisoprolol competitively blocks beta-1 adrenoceptors, reducing heart rate and myocardial contractility, thereby lowering blood pressure and myocardial oxygen demand.
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep in the original packaging.