Uses

Used to relieve smooth muscle spasm in irritable bowel syndrome, painful menstruation, and other conditions involving gastrointestinal or genitourinary smooth muscle spasm.

Do not use if

Contraindicated in patients with known hypersensitivity to alverine. Use with caution in patients with hepatic impairment.

Side effects

Generally well tolerated. Reported side effects include nausea, dizziness, headache, pruritus, rash, and rarely hepatotoxicity.

Warnings

Rare cases of hepatotoxicity have been reported; discontinue if signs of liver damage appear. Not recommended in pregnancy and lactation unless clearly necessary.

How it works

Alverine citrate is a direct-acting antispasmodic that relaxes smooth muscle by inhibiting calcium ion influx and acting as a selective serotonin (5-HT1A) receptor antagonist, reducing abnormal contractility.

Storage

Store below 25°C in a dry place, away from direct light. Keep out of reach of children.