Uses

BTK inhibitor used for chronic lymphocytic leukemia, small lymphocytic lymphoma, Waldenström macroglobulinemia, and chronic graft-versus-host disease after prior therapy.

Do not use if

No specific contraindications are listed in the referenced labeling.

Side effects

Common adverse effects include bleeding, infections, cytopenias, diarrhea, fatigue, hypertension, and cardiac arrhythmias.

Warnings

Monitor for bleeding, infections, arrhythmias, heart failure, and hypertension during treatment.

How it works

Ibrutinib irreversibly inhibits Bruton tyrosine kinase, disrupting B-cell receptor signaling and malignant B-cell survival.

Storage

Store at controlled room temperature in the original container.