Uses

Used for treatment and prevention of osteoporosis, glucocorticoid-induced osteoporosis, and Paget's disease of bone.

Do not use if

Contraindicated in esophageal disorders delaying emptying, inability to remain upright for 30 minutes, and hypocalcemia.

May cause esophageal irritation, abdominal pain, musculoskeletal pain, hypocalcemia, and rare osteonecrosis of the jaw.

Follow administration instructions carefully to reduce esophageal injury. Correct hypocalcemia before treatment.

Alendronate is a bisphosphonate that inhibits osteoclast-mediated bone resorption and increases bone density.

Store at 15–30°C in a tightly closed container.