esbriet 267 mg 270 capsules
اسبريت كبسول 267 مجم 270 كبسولة
pirfenidoneThe published official price. Pharmacies may differ slightly.
- Strength
- 267mg
- Form
- capsule
- Manufacturer
- f.hoffman la roche
- Route
- oral.solid
The medical information below is guidance and may be incomplete or wrong. Do not change your medicine or dose based on it — ask a pharmacist or doctor.
Uses
Pirfenidone is indicated for the treatment of idiopathic pulmonary fibrosis (IPF) in adults. It is used to slow the progression of this chronic, progressive lung disease.
Do not use if
There are no absolute contraindications listed in the FDA label. Use with caution in patients with hepatic impairment.
Side effects
Common adverse effects include nausea, rash, photosensitivity reactions, fatigue, diarrhea, and dyspepsia. Liver enzyme elevations and drug-induced liver injury have been reported. Severe cutaneous adverse reactions may occur.
Warnings
Monitor liver function tests (ALT, AST, bilirubin) before and during therapy due to risk of drug-induced liver injury. Patients should avoid prolonged sun exposure and use sunscreen due to photosensitivity risk. Severe cutaneous adverse reactions have been reported.
How it works
The exact mechanism of action of pirfenidone in IPF has not been fully established. It is a pyridone compound believed to have antifibrotic and anti-inflammatory properties, reducing the production of growth factors and cytokines involved in fibrosis.
Storage
Store at controlled room temperature (20–25°C). Keep away from moisture and direct light.