Uses

Used for multiple advanced or metastatic cancers, including renal cell carcinoma, melanoma, lung cancer, and other approved malignancies. It may be used alone or in combination with other anticancer therapies.

Do not use if

No formal contraindications are listed. Use is generally avoided in patients with severe hypersensitivity to nivolumab or its components.

Side effects

Fatigue, rash, diarrhea, musculoskeletal pain, and pruritus are common. Severe immune-mediated reactions affecting the lungs, liver, intestines, endocrine glands, or other organs may occur.

Warnings

May cause severe or fatal immune-mediated adverse reactions. Patients require close monitoring for organ-specific toxicity.

How it works

Nivolumab is a monoclonal antibody that blocks the PD-1 receptor, enhancing T-cell mediated antitumor immune responses.

Storage

Store refrigerated at 2°C to 8°C. Protect from light and do not freeze.