Uses

Used for certain EGFR-expressing colorectal cancers and squamous cell carcinoma of the head and neck. May be used alone or with other cancer therapies.

Do not use if

No absolute labeled contraindications, but severe hypersensitivity reactions require permanent discontinuation.

Side effects

Common effects include acneiform rash, infusion reactions, fatigue, diarrhea, and electrolyte abnormalities. Serious cardiopulmonary events may occur.

Warnings

Serious infusion reactions, cardiopulmonary arrest, pulmonary toxicity, and severe skin toxicity may occur.

How it works

A monoclonal antibody that binds EGFR and inhibits signaling involved in tumor growth and proliferation.

Storage

Store refrigerated at 2–8°C. Do not freeze or shake.