Uses

This combination has been used as a bronchodilator in bronchial asthma and chronic obstructive airway disorders. Its use is considered outdated in many settings.

Do not use if

Contraindicated in hypersensitivity to xanthines or barbiturates, porphyria, severe hepatic impairment, or a history of barbiturate dependence.

Side effects

May cause tachycardia, palpitations, nausea, headache, insomnia, irritability, sedation, dizziness, and dependence with prolonged phenobarbital exposure.

Warnings

Phenobarbital may impair alertness and carries a risk of dependence. Use cautiously in elderly patients and those with cardiovascular disease or significant drug interactions.

How it works

Acefylline piperazine is a xanthine derivative with bronchodilator activity. Phenobarbital is a barbiturate with central nervous system depressant effects.

Storage

Store below 25°C in a dry place away from light.