normapafenone 300 mg 10 f.c. tabs
نورمابافينون 300مجم 10 اقراص
propafenoneThe published official price. Pharmacies may differ slightly.
- Strength
- 300 mg
- Form
- tablet
- Manufacturer
- international drug agency (idi) > biocapital pharma
- Route
- oral.solid
The medical information below is guidance and may be incomplete or wrong. Do not change your medicine or dose based on it — ask a pharmacist or doctor.
Uses
Class IC antiarrhythmic agent indicated to prolong the time to recurrence of symptomatic paroxysmal atrial fibrillation in patients without structural heart disease. Also used for ventricular and supraventricular arrhythmias.
Do not use if
Contraindicated in heart failure, cardiogenic shock, sinoatrial or atrioventricular block without a pacemaker, known Brugada syndrome, bradycardia, severe hypotension, bronchospastic disorders, and electrolyte imbalance.
Side effects
Common side effects include dizziness, palpitations, chest pain, dyspnoea, taste disturbances (metallic taste), nausea, fatigue, and constipation. Pro-arrhythmic effects are a serious concern.
Warnings
Carries a serious warning regarding increased mortality risk in patients with non-life-threatening ventricular arrhythmias post-myocardial infarction (CAST study). Avoid use in structural heart disease. Monitor ECG and electrolytes during therapy.
How it works
Propafenone is a Class IC antiarrhythmic with local anaesthetic properties. It reduces the upstroke velocity (Phase 0) of the myocardial action potential by blocking fast sodium channels, slowing conduction velocity in the His-Purkinje system and ventricular myocardium. It has weak beta-blocking and calcium channel-blocking activity.
Storage
Store at 20–25°C (68–77°F) in a tightly closed container, away from moisture and heat.