malignomide 50 mg 28 f.c. tabs
ماليجنوميد 50مجم 28 قرص
bicalutamideThe published official price. Pharmacies may differ slightly.
- Strength
- 50 mg
- Form
- tablet
- Manufacturer
- hikma specialized pharmaceuticals
- Route
- oral.solid
The medical information below is guidance and may be incomplete or wrong. Do not change your medicine or dose based on it — ask a pharmacist or doctor.
Uses
A non-steroidal antiandrogen indicated in combination with a luteinizing hormone-releasing hormone (LHRH) analog for the treatment of Stage D2 metastatic carcinoma of the prostate.
Do not use if
Contraindicated in patients with known hypersensitivity to bicalutamide or any component of the tablet. Contraindicated in women; it has no indication for female patients.
Side effects
Common adverse reactions (occurring in more than 10% of patients) include hot flashes, pain, back pain, asthenia, pelvic pain, constipation, nausea, diarrhea, hematuria, and gynecomastia. Severe hepatic injury and fatal hepatic failure have been reported rarely.
Warnings
Severe hepatic injury and fatal hepatic failure have been reported. Monitor serum transaminase levels before starting treatment, at monthly intervals for the first four months, and periodically thereafter. Discontinue if jaundice or marked elevations in liver enzymes occur.
How it works
Bicalutamide is a non-steroidal androgen receptor inhibitor that competitively blocks the binding of androgens to cytosolic androgen receptors in target tissues. By inhibiting androgen action, it reduces the androgenic stimulation of prostate cancer cells, which are known to be androgen-sensitive.
Storage
Store at controlled room temperature, 20°C to 25°C (68°F to 77°F).