Uses

Topical formulations are used to reduce unwanted facial hair growth. Oral formulations may be used to reduce relapse risk in specific patients with high-risk neuroblastoma.

Do not use if

No formal contraindications are established in the referenced labeling.

Side effects

Topical use may cause skin irritation, acne, rash, or burning. Oral therapy may be associated with hearing loss, diarrhea, fever, infections, myelosuppression, and liver abnormalities.

Warnings

For oral oncology use, monitor blood counts, liver function, and hearing during treatment. For topical use, avoid contact with eyes and discontinue if severe irritation occurs.

How it works

An irreversible inhibitor of ornithine decarboxylase that reduces polyamine synthesis and affects cellular proliferation.

Storage

Store at 20–25°C.