Uses

Multi-symptom cold and flu preparation indicated for temporary relief of cough, runny nose, sneezing, sore throat, fever, minor aches, and pains associated with the common cold and influenza.

Do not use if

Contraindicated in patients taking MAO inhibitors or within 2 weeks of stopping them. Contraindicated with other acetaminophen-containing products. Avoid in patients with severe hepatic disease or known hypersensitivity to any component.

Side effects

Common side effects include drowsiness, dizziness, dry mouth, and constipation from doxylamine. Paracetamol is generally well tolerated at therapeutic doses but may cause liver injury in overdose. Nausea and gastrointestinal upset are possible.

Warnings

Contains acetaminophen: severe liver damage may occur if more than 4000 mg is taken in 24 hours or when combined with other acetaminophen-containing products or with chronic heavy alcohol use. Causes drowsiness; avoid alcohol and activities requiring alertness. Store between 20–25°C and do not refrigerate.

How it works

Paracetamol (acetaminophen) provides analgesia and antipyresis via inhibition of central prostaglandin synthesis. Dextromethorphan suppresses the medullary cough center via sigma-1 and NMDA receptor activity. Doxylamine is a first-generation H1-antihistamine that reduces rhinorrhea and sneezing and promotes sleep through central sedation.

Storage

Store between 20–25°C (68–77°F). Do not refrigerate.