Uses

Used for osteoporosis in postmenopausal women and men, prevention of glucocorticoid-induced osteoporosis, and Paget's disease of bone.

Do not use if

Contraindicated in hypocalcemia, severe renal impairment, and hypersensitivity to zoledronic acid or its components.

Common effects include fever, muscle pain, headache, joint pain, nausea, and flu-like symptoms.

Monitor calcium levels and renal function. Adequate calcium and vitamin D supplementation is usually required.

A bisphosphonate that inhibits osteoclast-mediated bone resorption, increasing bone density and reducing fracture risk.

Store at 20–25°C. Protect from extreme temperatures.