Uses

Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Do not use if

Contraindicated in severe renal impairment, metabolic acidosis, diabetic ketoacidosis, and hypersensitivity to components.

May cause diarrhea, nausea, abdominal pain, headache, and upper respiratory symptoms.

Monitor for lactic acidosis, pancreatitis, heart failure, and renal dysfunction.

Alogliptin enhances incretin activity while metformin reduces hepatic glucose production and improves insulin sensitivity.

Store at 15–30°C in a tightly closed container.