Uses

Combination indicated for the relief of acute musculoskeletal pain and inflammation associated with muscle spasm, such as low back pain and sprains.

Do not use if

Contraindicated in patients with peptic ulcer disease, renal or hepatic impairment, known allergy to NSAIDs or aspirin, and in the third trimester of pregnancy. Avoid in patients with myasthenia gravis.

Side effects

May cause gastrointestinal upset, nausea, dizziness, drowsiness, and headache. Diclofenac carries cardiovascular and renal risks; methocarbamol may cause sedation and blurred vision.

Warnings

NSAIDs increase the risk of serious cardiovascular thrombotic events and gastrointestinal bleeding. Use the lowest effective dose for the shortest duration. Caution in elderly patients.

How it works

Diclofenac inhibits cyclooxygenase (COX-1 and COX-2), reducing prostaglandin synthesis to exert anti-inflammatory and analgesic effects. Methocarbamol acts as a central nervous system depressant that relieves skeletal muscle spasm.

Storage

Store below 30°C in a dry place, protected from light and moisture.