Uses

Used for treatment and prevention of tuberculosis caused by susceptible organisms. Active tuberculosis requires combination therapy.

Do not use if

Contraindicated in acute liver disease, prior severe isoniazid-induced hepatic injury, and severe hypersensitivity reactions.

Common adverse effects include hepatotoxicity, peripheral neuropathy, rash, and gastrointestinal disturbances.

Severe and potentially fatal hepatitis may occur. Liver function monitoring is important during therapy.

An antitubercular agent that inhibits mycolic acid synthesis in Mycobacterium tuberculosis.

Store at room temperature in a tightly closed container.